FMS Research Center

Angewandte Chemie Int. Ed. publication by professors Sijbren Otto, Anna Hirsch and collaborators

A collaboration between professors Anna K.H. Hirsch (RUG), Sijbren Otto (RUG), and other colleagues from the University of Groningen, has been recently published their work in Angewandte Chemie International Edition.

Publication details:

Milon Mondal, Nedyalka Radeva, Hugo Fanlo-Virgos, Sijbren Otto, Gerhard Klebe, and Anna K.H. Hirsch, Fragment linking and optimization of inhibitors of the aspartic protease endothiapepsin: fragment-based drug design facilitated by dynamic combinatorial chemistry, Angew. Chem. Int. Ed. (2016) 55, 1-6